Preheat the oven to 350F.

In a large bowl, beat the butter and brown sugar until fluffy. Beat in the egg and vanilla. Add the flour, oat bran, wheat germ, baking powder, baking soda and salt and stir until the batter starts to come together; add the chocolate chips, cranberries and walnuts and stir or beat on low speed just until the batter is combined.

Drop the dough in large spoonfuls onto a cookie sheet that has been sprayed with nonstick spray or lined with parchment; flatten each cookie a little with your hand or the back of a fork. Bake for 12-14 minutes, until just set around the edges but still soft in the middle. Transfer to a wire rack to cool.